代表性研究论文
1.Danyi Lu, Zhigang Wang*, Baojian Wu*. Pharmacokinetics-based Chronotherapy. Current Drug Metabolism. 2022. DOI: 10.2174/1389200223666220106124218
2. Yi Wang#, Zhigang Wang#, Zhengping Wu, Menglin Chen, Dong Dong, Pei Yu, Danyi Lu*, Baojian Wu*. Involvement of REV-ERBα dysregulation and ferroptosis in aristolochic acid I-induced renal injury. Biochemical Pharmacology. 2021.193: 114807.
3. Meiqing Li#, Danyi Lu#, Yulian Cheng#, Chunlei Wu, Jianchao Zhang, Wenli Shi, Zhihao Ding, Yanyan Li, Binghua Cheng, Xian Lin, Ximing Shao, Hongchang Li, Lijing Fang*, Ke Liu*, Wu Su*. A novel pyrrole-imidazole polyamide targets Aurora kinase A and suppresses tumor growth in vivo. Biochemical and Biophysical Research Communications. 2021.571:167-173.
4. Wenli Shi#, Danyi Lu#, Chunlei Wu, Meiqing Li, Zhihao Ding, Yanyan Li, Binghua Chen, Xian Lin, Wu Su, Ximing Shao, Zhihui Xia, Lijing Fang*, Ke Liu*, Hongchang Li*. Coibamide A kills cancer cells through inhibiting autophagy. Biochemical and Biophysical Research Communications. 2021.547:52-58.
5. Huan Zhao, Yongbin Tong, Danyi Lu*, Baojian Wu*. Circadian clock regulates hepatotoxicity of Tripterygium wilfordii through modulation of metabolism. Journal of Pharmacy and Pharmacology. 2020.72(12):1854-1864.
6.Danyi Lu#, Mengjing Zhao#, Min Chen, Baojian Wu*. Circadian clock-controlled drug metabolism: Implications for chronotherapeutics. Drug Metabolism and Disposition. 2020.48(5):395-406. (封面论文)
7.Danyi Lu#, Dong Dong#, Qian Xie, Zhijie Li, Baojian Wu*. Disposition of mianserin and cyclizine in UGT2B10-overexpressing human embryonic kidney 293 cells: identification of UGT2B10 as a novel N-glucosidation enzyme and breast cancer resistance protein as an N-glucoside transporter. Drug Metabolism and Disposition. 2018.46(7):970-979.
8.Danyi Lu, Dong Dong*, Baojian Wu*. Highly selective N-glucuronidation of four piperazine-containing drugs by UDP-glucuronosyltransferase 2B10. Expert Opinion on Drug Metabolism & Toxicology. 2018.14(9):989-998.
9.Danyi Lu, Shuai Wang, Qian Xie, Lianxia Guo, Baojian Wu*. Transcriptional regulation of human UDP-Glucuronosyltransferase 2B10 by farnesoid X receptor in human hepatoma HepG2 cells. Molecular Pharmaceutics. 2017.14(9):2899-2907.
10.Danyi Lu#, Qian Xie#, Baojian Wu*. N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate identification. Journal of Pharmaceutical and Biomedical Analysis. 2017.145:692-703.
11.Danyi Lu#, Hui Liu#, Wencai Ye, Ying Wang, Baojian Wu*. Structure- and isoform-specific glucuronidation of six curcumin analogs. Xenobiotica. 2017.47(4):304-313.
12. Dong Dong#, Tianpeng Zhang#, Danyi Lu#, Jie Liu, Baojian Wu*. In vitro characterization of belinostat glucuronidation: demonstration of both UGT1A1 and UGT2B7 as the main contributing isozymes. Xenobiotica. 2017.47(4):277-283.
13.Danyi Lu#, Zhiguo Ma#, Tianpeng Zhang, Xingwang Zhang, Baojian Wu*. Metabolism of the anthelmintic drug niclosamide by cytochrome P450 enzymes and UDP-glucuronosyltransferases: metabolite elucidation and main contributions from CYP1A2 and UGT1A1. Xenobiotica. 2016.46(1):1-13.
14.Danyi Lu#, Dong Dong#, Zhong Liu, Yifei Wang*, Baojian Wu*. Metabolism elucidation of BJ-B11 (a heat shock protein 90 inhibitor) by human liver microsomes: identification of main contributing enzymes. Expert Opinion on Drug Metabolism & Toxicology. 2015.11(7):1029-40.
15.Danyi Lu, Jiayu Zhang, Zhenya Yang, Hongming Liu, Sha Li, Baojian Wu*, Zhiguo Ma*. Quantitative analysis of Cistanches Herba using high-performance liquid chromatography coupled with diode array detection and high-resolution mass spectrometry combined with chemometric methods. Journal of Separation Science, 2013, 36(12): 1945-1952.
