黄晓其
中药学副研究员,硕士研究生导师。国家自然科学基金通讯评审专家,广东省科技项目评审专家,中国中医药研究促进会青年医师分会常务理事,中国中医药研究促进会药物经济学与药物评价专委会委员,中国中医药信息学会科技创新与成果转化分会理事,广东省省呼吸与健康学会生物医药大数据专委会副主任委员,广东省药理学会内分泌代谢病药理专业委员会常务委员,广东省中西医结合学会中药专业委员会常务委员。主持并参与国家自然科学基金面上项目、国家科技重大专项、广东省重大科技专项、广东省教育部产学研结合重点项目、广东省自然科学基金面上项目等国家级、省级课题多项。作为主要研究者参与3个中药老六类新药临床前研究和多个中药化妆品、功能食品和日化用品等中药健康产品的研发。发表论文65篇(SCI收录27篇),参与著书2册,参与授权发明专利5项,申请专利2项。指导两项本科生作品荣获第八届“挑战杯”广东大学生创业计划竞赛银奖,并指导多名本科生完成国家级、省级大学生创新创业项目。曾荣获广州亚运会、亚残运会志愿者工作先进个人,广州中医药大学亚运志愿者工作突出贡献奖,广州中医药大学优秀党支部书记。
E-mail: huangxiaoqi@gzucm.edu.cn代表性研究论文
1.Xiaoyan Wu, Ronglei Huang, Gaoxiang Ai, Hanbin Chen, Xingdong Ma, Jiana Zhang, Qiting Huang, Jiayi Lao, Huiyuan Zeng, Chuwen Li, Jianhui Xie, Yucui Li, Ziren Su, Jiannan Chen*, Xiaoqi Huang*. 9-Hydroxy-8-oxypalmatine, a novel liver- mediated oxymetabolite of palmatine, alleviates hyperuricemia and kidney inflammation in hyperuricemic mice[J], Journal of Ethnopharmacology 2024(335): 118606.
2.Li MY, Wu YZ, Qiu JG, Lei JX, Li MX, Xu N, Liu YH, Jin Z, Su ZR, Lee SM,Zheng XB*, Xiao-Qi Huang*. Huangqin Decoction ameliorates ulcerative colitis by regulating fatty acid metabolism to mediate macrophage polarization via activating FFAR4-AMPK-PPARα pathway[J], Journal of Ethnopharmacology 2023(311):116430.
3.Juanjuan Cheng, Xingdong Ma, Haitao Zhang, Xiaoyan Wu, Minhua Li, Gaoxiang Ai, Ruoting Zhan, Jianhui Xie, Ziren Su*, Xiaoqi Huang*. 8-Oxypalmatine, a novel oxidative metabolite of palmatine, exhibits superior anti-colitis effect via regulating Nrf2 and NLRP3 inflammasome[J], Biomedicine&Pharmacotherapy,2022 (153):113335.
4.Mu-xia Li1, Min-yao Li1, Jun-xuan Lei, Yu-zhu Wu, Ze-hao Li, Lin-ming Chen, Chang-lin Zhou, Ji-yan Su, Guo-xin Huang, Xiao-qi Huang*, Xue-bao Zheng*, Huangqin decoction ameliorates DSS-induced ulcerative colitis: Role of gut microbiota and amino acid metabolism, mTOR pathway and intestinal epithelial barrier[J], Phytomedicine, 2022(100):154052.
5.Min-yao Li,Mu-xia Li, Nan Xu,Ze-hao Li,Yao-min Zhang,Yu-xuan Gan,Hui-juan Luo,Chang-lin Zhou,Yu-hong Liu,Zi-ren Su,Xiao-qi Huang* and Xue-bao Zheng*. Effects of Huangqin Decoction on Ulcerative Colitis by Targeting Estrogen Receptor Alpha and Ameliorating Endothelial Dysfunction Based on System Pharmacology[J], Journal of Ethnopharmacology, 2021(271): 113886.
6.Min-yao Li, Hui-juan Luo, Xue Wu, Yu-hong Liu, Yu-xuan Gan, Nan Xu,Yao-min Zhang, Shu-hua Zhang, Chang-lin Zhou, Zi-ren Su, Xiao-qi Huang* and Xue-bao Zheng*. Anti-Inflammatory Effects of Huangqin Decoction on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice Through Regulation of the Gut Microbiota and Suppression of the Ras-PI3K-Akt-HIF-1α and NF-κB Pathways[J], Frontiers in Pharmacology, 2020(10): 1552.
7.Xiaoqi Huang1, Zhiwei Chen1, Minyao Li, Yaomin Zhang Shijie Xu, Haiyang Huang, Xiaoli Wu* , Xuebao Zheng*. Herbal pair Huangqin-Baishao: mechanismsunderlying inflammatory bowel disease bycombined system pharmacology and cellexperiment approach[J], BMC Complementary Medicine and Therapies, 2020(20): 292.
8.Yuxuan Gan, Gaoxiang Ai, Jiazhen Wu, Huijuan Luo, Liping Chen, Qionghui Huang, Xue Wu, Nan Xu, Minyao Li, Ziren Su, Yuhong Liu*, Xiaoqi Huang*. Patchouli oil ameliorates 5-fluorouracil-induced intestinal mucositis in rats via protecting intestinal barrier and regulating water transport[J], Journal of Ethnopharmacology, 2020(250): 112519.
9.邱建国,邱一桐,李国荣,张林生,郑雪,姚泳江,王熙丹,黄海阳,张凤敏,苏冀彦,郑学宝#,黄晓其#.黄芩汤通过调控内质网应激减轻小鼠溃疡性结肠炎[J].南方医科大学学报,2024, 44(11): 2172-2183.
10.李敏瑶,张耀敏,李泽豪,周福生,郑学宝,苏子仁,黄海阳,金真,许仕杰,黄晓其#.基于网络药理学和细胞实验探讨六味顺激方治疗肠易激综合征的作用[J].中成药,2023,45(03):987-998.
11.吴玉竹,李敏瑶,邱建国,雷骏轩,孙泽佳,濮声乐,王小林,郑学宝#,黄晓其#.黄芩汤治疗慢性复发型溃疡性结肠炎大肠湿热证小鼠的作用机制研究[J].中药新药与临床药理,2022,34(08):1083-1094.