2004－至今 广州中医药大学，研究员

2000－2004 德国图宾根（Tuebingen）大学，生物药学，博士

1999－2000  同济大学留德预备部，进修生

1995－1999  广州中医药大学，助教、讲师

1992－1995  中山大学，分析化学，硕士

1988－1992  中山大学，化学，学士

五环三萜类化合物生物合成途径解析

中药污染真菌毒素的快速检测及预警方法研究

1. 广州市科技计划项目-重点研发计划农业和社会科技项目 2023-2026，主持

2. 广州中医药大学专业学位研究生教学案例库建设培育项目 2023-2024，主持

3. 广东省自然科学基金面上项目  2015-2019，主持

4. 广东省高水平大学建设项目（校内） 2017-2018，主持

5. 广东省科技计划项目-科技服务业关键共性技术与产品研发专题 2016-2018，主持

1. Liang Y, Lu H, Tang J, Ye X, Wei Y, Liao B, Liu L*, Xu H*. ActO, a positive cluster-situated regulator for actinomycins biosynthesis in Streptomyces antibioticus ZS. Gene. 2025 Jan 15;933:148962. doi: 10.1016/j.gene.2024.148962. Epub 2024 Sep 24.

2.Li L, Lin S, Chen Y, Wang Y, Xiao L, Ye X, Sun L, Zhan R*, Xu H*. Cytochrome P450 Monooxygenase/Cytochrome P450 Reductase Bi-Enzymatic System Isolated from Ilex asprella for   Regio-Specific Oxidation of Pentacyclic Triterpenoids. Front Plant Sci. 2022 Mar 24;13:831401.

3.Ji X, Lin S, Chen Y, Liu J, Yun X, Wang T, Qin J, Luo C, Wang K, Zhao Z, Zhan R*, Xu H*. Identification of α-Amyrin 28-Carboxylase and Glycosyltransferase from Ilex asprella and Production of Ursolic Acid 28-O-β-D-Glucopyranoside in Engineered Yeast. Front Plant Sci. 2020 May 20;11:612.

4.Huang A, Chi Y, Liu J, Wang M, Qin J, Ou L, Chen W, Zhao Z, Zhan R*, Xu H*. Profiling and Pharmacokinetic Studies of Alkaloids in Rats After Oral Administration of Zanthoxylum nitidum Decoction by UPLC-Q-TOF-MS/MS and HPLC-MS/MS. Molecules. 2019 Feb 7;24(3).

5.Lu X, Luo C, Xing J, Han Z, Li T, Wu W, Xu H*, Zhan R, Chen W. Optimization of Storage Conditions of the Medicinal Herb Ilex asprella against the Sterigmatocystin Producer Aspergillus versicolor Using Response Surface Methodology. Toxins (Basel). 2018 Nov 27;10(12).

6.Wen L, Yun X, Zheng X, Xu H*, Zhan R, Chen W, Xu Y, Chen Y, Zhang J. Transcriptomic Comparison Reveals Candidate Genes for Triterpenoid Biosynthesis in Two Closely Related Ilex Species. Front Plant Sci. 2017 Apr 28;8:634.

7.Huang A, Xu H*, Zhan R, Chen W, Liu J, Chi Y, Chen D, Ji X, Luo C. Metabolic Profile of Skimmianine in Rats Determined by Ultra-Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Tandem Mass Spectrometry. Molecules. 2017 Mar 23;22(4).

8.Zheng RS, Wang WL, Tan J, Xu H*, Zhan RT, Chen WW. An investigation of fungal contamination on the surface of medicinal herbs in China. Chin Med. 2017 Jan 3;12:2.

9.Zheng X, Luo X, Ye G, Chen Y, Ji X, Wen L, Xu Y, Xu H*, Zhan R, Chen W*. Characterisation of two oxidosqualene cyclases responsible for triterpenoid biosynthesis in Ilex asprella. Int J Mol Sci. 2015 Feb 5;16(2):3564-78.

10.Zheng R, Xu H*, Wang W, Zhan R, Chen W. Simultaneous determination of aflatoxin B(1), B(2), G(1), G(2), ochratoxin A, and sterigmatocystin in traditional Chinese medicines by LC-MS-MS. Anal Bioanal Chem. 2014 May;406(13):3031-9.

11.Zheng X, Xu H*, Ma X, Zhan R, Chen W*. Triterpenoid saponin biosynthetic pathway profiling and candidate gene mining of the Ilex asprella root using RNA-Seq. Int J Mol Sci. 2014 Apr 9;15(4):5970-87.