2020/8-至今，副研究员，广州中医药大学 中药学院 中药资源科学与工程研究中心

2017/7-2020/7，副研究员，广州中医药大学 科技创新中心

2014/11-2017/6，博士后，美国福克斯蔡司癌症研究中心

2009/10-2013/12，博士，中国科学院 动物研究所膜生物学国家重点实验室

2007/7-2009/9, 硕士，中国科学院 广州生物医药与健康研究院

1）中药抗肿瘤分子机制研究

2）肿瘤分子靶向治疗。

1. 广东省自然科学基金面上项目，2022A1515011881，化橘红有效成分通过靶向Skp2-SCF E3连接酶治疗非小细胞肺癌的作用机制研究，2022/01 至 2024/12，10万元, 在研, 主持。

2. 广东省区域联合基金地区培育项目，2021B1515140052, 基于Fanconi anemia通路介导化疗耐药研究鹅不食草及其有效成分联合顺铂治疗肺癌的作用机制，2021/10 至 2024/09，30万元, 在研, 主持。

3. 广东省医学科研基金面上项目，B2020014，F-box蛋白NIPA促进肺癌细胞增殖以及介导化疗耐药的分子机理研究，2020/07-2022/06，1.5万元，在研，主持。

4. 国家自然科学基金青年项目，小胶质细胞通过分泌IL-1β招募星形胶质细胞进而促进髓母细胞瘤发生的分子机理研究，81802776，2019/01-2021/12，21万元，已结题，主持。

5. 高水平大学建设杏林人才科研配套经费，2017.7-2020.7，40万元，主持。

主要承担《生物学》等课程。

1. Shangping Xing, Feifei Nong，Yaqin Wang, Da, Huang, Jialiang Qin, Yu-Fei Chen, Dan-Hua He, Pei-En Wu, Huicai Huang, Ruoting Zhan, Hui Xu, Yong-Qiang Liu*. Brusatol has therapeutic efficacy in non-small cell lung cancer by targeting Skp1 to inhibit cancer growth and metastasis. Pharmacological Research, 2022, 176: 106059.

2. Xiang-Zhen Fan, Yu-Fei Chen, Shi-Bing Zhang, Dan-Hua He, Su-Fen Wei, Qi Wang, Hua-Feng Pan*, Yong-Qiang Liu*. Centipeda minima extract sensitizes lung cancer cells to DNA-crosslinking agents via targeting Fanconi anemia pathway. Phytomedicine, 2021, 91: 153689.

3. Hailong Liu#, Youliang Sun#, Qian Zhang, Wei Jin, Renata E. Gordon, Yanyang Zhang, Jian Wang, Caihong Sun, Z.John. Wang, Xueling Qi, Junping Zhang, Boyuan Huang, Qiuping Gui, Hongyu Yuan, Ling Chen, Xiaodong Ma, Chuan Fang, Yong-Qiang Liu*, Xinguang Yu* and Shiyu Feng*. Pro-inflammatory and proliferative microglia drive progression of glioblastoma. Cell Reports, 2021, 36(11): 109718.

4. Dan-Hua He, Yu-Fei Chen, Yi-Le Zhou, Shi-Bing Zhang, Ming Hong, Xianjun Yu, Su-Fen Wei, Xiang-Zhen Fan, Si-Yi Li, Qi Wang, Yongzhi Lu*, Yong-Qiang Liu*. Phytochemical library screen reveals betulinic acid as a novel Skp2-SCF E3 ligase inhibitor in non-small cell lung cancer. Cancer Science, 2021, 112: 3218–3232.

5. Su-Fen Wei, Dan-Hua He, Shi-Bing Zhang, Yongzhi Lu, Xiaowei Ye, Xiang-Zhen Fan, Hong Wang, Qi Wang*, Yong-Qiang Liu*. Identification of pseudolaric acid B as a novel Hedgehog pathway inhibitor in medulloblastoma. Biochemical Pharmacology, 2021, 190: 114593.

6. Yong-Qiang Liu*, Xiao-Lu Wang, Dan-Hua He, Yong-Xian Cheng*. Protection against chemotherapy- and radiotherapy-induced side effects: mechanisms and therapeutic opportunities of phytochemicals. Phytomedicine, 2021, 80: 153402.

7. Yi-le Zhou#, Yong-ming Yan#, Si-yi Li, Dan-hua He, Sha Xiong, Su-fen Wei, Wei Liu, Ling Hu, Qi Wang, Hua-feng Pan*, Yong-xian Cheng*, Yong-Qiang Liu*. 6-O-angeloylplenolin exerts neuroprotection against lipopolysaccharide-induced neuroinflammation in vitro and in vivo. Acta Pharmacologica Sinica, 2020, 41: 10–21.

8. Si-Yi Li#, Yi-Le Zhou#, Dan-Hua He, Wei Liu, Xiang-Zhen Fan, Qi Wang, Hua-Feng Pan*, Yong-Xian Cheng*, Yong-Qiang Liu*. Centipeda minima extract exerts antineuroinflammatory effects via the inhibition of NF-κB signaling pathway. Phytomedicine, 2020, 67: 153164.

9. Yi-Jie Wang#, Xin-Yue Wang#, Xu-Yi Hao, Yong-Ming Yan, Ming Hong, Su-Fen Wei, Yi-Le Zhou, Qi Wang*, Yong-Xian Cheng*, Yong-Qiang Liu*. Ethanol Extract of Centipeda minima Exerts Antioxidant and Neuroprotective Effects via Activation of the Nrf2 Signaling Pathway. Oxidative Medicine and Cellular Longevity, 2019, 9421037.

10. Yongqiang Liu#, Larra Yuelling#, Yuan Wan, Fang Du, Renata E. Gordon, Jenny A. O'Brien, Jessica M.Y. Ng, Shannon Robins, Eric H. Lee, Hailong Liu, Tom Curran, Zeng-Jie Yang*. Astrocytes promote medulloblastoma progression through hedgehog secretion. Cancer Research, 2017, 77: 6692-6703.