姓名：吴锦俊

职称：副教授，硕士生导师

学位：博士

学院：中药学院

E-mail: wujinjun@gzucm.edu.cn

教育经历：

1. 2011/09-2016/06，广州中医药大学，中药学院，博士

2. 2007/09-2011/06，福建中医药大学，药学院，学士

工作经历：

1. 2023/11/19-至今，广州中医药大学，中药学院，副教授

2. 2020/01/01-2023/11/18，广州中医药大学，中药学院，副研究员

3. 2018/05/29--2019/05/28，美国密苏里大学，医学院，访问学者

4. 2016/09-2019/12，广州中医药大学，国际中医药转化医学研究所，讲师

研究领域：中药抗肿瘤药理学

奖励和荣誉：

1. 第五届全国高校教师教学创新大赛二等奖，2025.08

2. “新南方教学奖励基金”优秀教师，2025.07

3. 广东省第五届高校教师教学创新大赛特等奖，2025.06

4. 广州中医药大学优秀青年教师专职辅导员（班主任）称号，2025.04

5. 广州中医药大学第五届教学创新大赛特等奖，2025.03

6. 广东省第七届高校（本科）青年教师教学大赛一等奖，2024.12

7. 第八届全国医药院校药学/中药学专业大学生实验技能竞赛特等奖（第一指导老师），2024.12

8. 2024中俄创新医药前沿报告暨中俄医科大学联盟全球学术会议暨青年教师教学大赛特等奖，2024.11

9. 广州中医药大学教师讲课比赛一等奖，2024.11

10. 广东省高等学校教学管理学会本科人才培养改革与管理服务创新优秀典型案例，2024.09

11. 广州中医药大学教学设计竞赛一等奖，2024.08

12. 广州中医药大学中药学院教师讲课比赛一等奖，2024.06

13. 广州中医药大学第四届教学创新大赛二等奖，2024.03

14. 广东省科学技术奖科技进步奖一等奖（6/15），2020.02

15. 中国中西医结合学会科学技术奖二等奖（8/18），2016.12

主持科研项目：

1. 广东省中医药局面上项目，20251091，2025.01-2026.12

2. 2024年度“中药学院英才托举计划”B岗，2025.04-2027.04

3. 广州中医药大学青年拔尖人才（团队）培育“揭榜挂帅”项目，2024.06-2027.06

4. 2023年广东省普通高校特色创新类项目，2023KTSCX024，2024.01-2025.12

5. 广州市科学技术局基础与应用基础研究项目，202201011393, 2022.04-2024.03

6. 广东省中医药局面上项目，20211111，2021.01-2022.12

7. 广州中医药大学“青年英才”第四批培养对象，QNYC20190103，2020.04-2024.03

8. 国家自然科学基金青年科学基金项目，81703803，2018/01-2020/12

9. 广东省自然科学基金-博士科研启动项目，2017A030310464，2017.05-2020.05

10. 广东省普通高校青年创新人才项目，2016KQNCX026，2017/01-2019/01

代表性论文：

1. Yuting Zheng^#, Yinli Zheng#, Haipeng Chen#, Xuanjing Tan, Guiyu Zhang, Muyan Kong, Ruidi Jiang, Hong Yu, Keyao Shan, Jiyao Liu, Rong Zhang, Zhongqiu Liu*, Jinjun Wu*, Erianin triggers ferroptosis in colorectal cancer cells by facilitating the ubiquitination and degradation of GPX4, Phytomedicine. 2025, 139:156465.

2. Ying Zhang^#, Huan Lan^#, Wenjuan Zhai, Lin Jiang, Xiaotong Xia, Fang liu, Lin Zhang, Jinjun Wu*, Zhongqiu Liu*, Caiyan Wang*. Caffeic acid alleviates myocardialischemia-reperfusion injury by directlytargeting Keap1N532/M550 and promotingits degradation. Journal of Pharmaceutical Analysis, 2025, doi.org/10.1016/j.jpha.2025.101219.

3. Ruidi Jiang^#, Xuanjing Tan^#, Guiyu Zhang^#, Haipeng Chen, Hong Yu, Yuting Zheng, Muyan Kong, Keyao Shan, Jiyao Liu, Rong Zhang, Zhongqiu Liu*, Jinjun Wu*, Dendrobium officinale inhibits colorectal cancer progression by induction of glutathione peroxidase 4-mediated ferroptosis, Chinese Journal of Natural Medicines, doi: 10.1016/S1875-5364(25)60962-9.

4. Haipeng Chen^#, Yanmei Lou^#, Senyi Lin, Xuanjing Tan, Yuting Zheng, Hong Yu, Ruidi Jiang, Yijie Wei, Huijie Huang, Xiaoxiao Qi, Rong Zhang, Zhongqiu Liu*, Jinjun Wu*, Formononetin, a bioactive isoflavonoid constituent from Astragalus membranaceus (Fisch.) Bunge, ameliorates type 1 diabetes mellitus via activation of Keap1/Nrf2 signaling pathway: An integrated study supported by network pharmacology and experimental validation, Journal of Ethnopharmacology. 2024, 322:117576.

5. Yinli Zheng^#, Leyan Li^#, Haipeng Chen^#, Yuting Zheng, Xuanjing Tan, Guiyu Zhang, Ruidi Jiang, Hong Yu, Senyi Lin, Yijie Wei, Ying Wang, Rong Zhang, Zhongqiu Liu*, Jinjun Wu* Luteolin exhibits synergistic therapeutic efficacy with erastin to induce ferroptosis in colon cancer cells through the HIC1-mediated inhibition of GPX4 expression, Free Radical Biology and Medicine, 2023, 208:530-544.

6. AiJia Ji^#, Qing Ma^#, MuYan Kong, LeYan Li, XinLian Chen, ZhongQiu Liu, JinJun Wu*, RongRong Zhang*, Two cardenolide glycosides from the seed fairs of Asclepia curassavica and their cytotoxic activities, Chinese Journal of Natural Medicines. 2022, 20(3): 202-209.

7. Yinli Zheng^#, Jinjun Wu^#, Ru Deng^#, Censhan Lin^#, Yuhua Huang, Xia Yang, Chunhua Wang, Mingming Yang, Yangfan He, Jiabin Lu, Xiaodong Su, Qian Yan, Yinghui Zhu, Xinyuan Guan, Yan Li, Jingping Yun, G3BP2 regulated by the lncRNA LINC01554 facilitates esophageal squamous cell carcinoma metastasis through stabilizing HDGF transcript, Oncogene. 2022, 41(4):515-526.

8. Lin An, Yuefang Lin, Leyan Li, Muyan Kong, Yanmei Lou, Jinjun Wu*, Zhongqiu Liu^*, Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis. Frontiers in Pharmacology, 2021, 11: 618262.

9. Muyan Kong, Leyan Li, Yanmei Lou, Hongyu Chi, Jinjun Wu*. Chinese herbal medicines in the prevention and treatment of colorectal cancer: from molecular mechanisms to potential clinical applications. Journal of Integrative Medicine. 2020, 18(5):369-384.

10. Yanmei Lou^#, Zhenzhen Guo^#, Yuanfeng Zhu^#, Muyan Kong, Rongrong Zhang, Linlin Lu, Feichi Wu, Zhongqiu Liu^*, Jinjun Wu^*, Houttuynia cordata Thunb. and its bioactive compound 2-undecanone significantly suppress benzo(a)pyrene-induced lung tumorigenesis by activating the Nrf2-HO-1/NQO-1 signaling pathway, Journal of Experimental & Clinical Cancer Research, 2019, 38:242.

11. Yanmei Lou^#, Zhenzhen Guo^#, Yuanfeng Zhu, Guiyu Zhang, Ying Wang, Xiaoxiao Qi, Linlin Lu, Zhongqiu Liu^*, Jinjun Wu^*, Astragali radix and its main bioactive compounds activate the Nrf2-mediated signaling pathway to induce P-glycoprotein and breast cancer resistance protein, Journal of Ethnopharmacology, 2019, 228: 82-91.

12. Jinjun Wu, Zhenzhen Guo, Yuanfeng Zhu, Zhijian Huang, Xia Gong, Yuhuan Li, Wenjie Son, Xiaoyan Li, Yanmei Lou, Lijun Zhu, Linlin Lu, Zhongqiu Liu^*, Liang Liu^*, A systematic review of pharmacokinetic studies on herbal drug Fuzi: implications for Fuzi as personalized medicine, Phytomedicine, 2018, 44:187-203.

13. Jinjun Wu, Yuanfeng Zhu, Zhenzhen Guo, Yanmei Lou, Shugui He, Yang Guan, Lijun Zhu, Zhongqiu Liu, Linlin Lu^*, Liang Liu^*, Aconitum alkaloids, the major components of Aconitum species, affect expression of multidrug resistance-associated protein 2 and breast cancer resistance protein by activating the Nrf2-mediated signalling pathway, Phytomedicine, 2018, 44:87-97.