教育经历

(1) 2015-09至2018-06，广州中医药大学，中药学院，博士，导师：周联

(2) 2013-09至2015-06，广州中医药大学，中药学院，硕士，导师：林吉

(3) 2011-09-2013-06，广东药科大学，中药学院，本科

工作经历

2018/07--至今，广州中医药大学，中药学院，学校引进“杏林青年学者”

中药防治溃疡性结肠炎及肠炎性结肠癌的药效及作用机制

1. mTORC1调控HK1介导巨噬细胞代谢重编程在铁皮石斛多糖防治溃疡性结肠炎中的作用机制,国家青年科学基金项目；(82004025)，2021.01.01-2023.12.31.

2. 车叶草苷通过VDR抑制内质网应激介导的巨噬细胞代谢异常防治UC的机制研究，广东省基础与应用基础研究基金项目；(2019A1515110561)，2020.01.01-2021.12.31

• [1] Jian Liang#, Hailun Li#, Jianqiang Chen#, Lian He, Xianhua Du, Lian Zhou, Qingping Xiong, Xiaoping Lai, Yiqi Yang*, Song Huang*, Shaozhen Hou*. Dendrobium officinale polysaccharides alleviate colon tumorigenesis via restoring intestinal barrier function and enhancing anti-tumor immune response [J]. Pharmacological Research, 2019.104417. (SCI，JCR一区，IF: 5.893).

  [2] Yiqi Yang, Yanfang Wu, Fangfang Xu, Jinbao Deng, Lilan Wu, Jian Liang*, Dean Guo*, Bo Liu*. Tripterigium glycoside fraction n2: Alleviation of DSS-induced colitis by modulating immune homeostasis in mice [J]. Phytomedicine, 2019, 58, 152855. (SCI, IF: 4.268, JCR Q1, 并列通讯).

  [3] Jian Liang#, Yanfang Wu#, Han Yuan#, et al. Dendrobium officinale polysaccharides attenuate learning and memory disabilities via anti-oxidant and anti-inflammatory actions [J]. International Journal of Biological Macromolecules, 2019, 126. 414-426. (SCI，JCR一区，IF: 5.162).

  [4] Jian Liang#, Shuxian Chen#, Jianhui Chen#, et al. Therapeutic roles of polysaccharides from Dendrobium Officinaleon, colitis and its underlying mechanisms [J]. Carbohydrate Polymers, 2018, 185:159–168. (SCI，中科院一区，IF: 7.182).

  [5] Jian Liang#, Shuxian Chen#, Youdong Hu#, et al. Protective roles and mechanisms of Dendrobium officinal polysaccharides on secondary liver injury in acute colitis [J]. International Journal of Biological Macromolecules, 2018, 107: 2201-2210. (SCI，JCR一区，IF: 5.162).

  [6] Jian Liang#, Jiwang Liang#, Hairong Hao#, et al. The Extracts of Morinda officinalis and Its Hairy Roots Attenuate Dextran Sodium Sulfate-Induced Chronic Ulcerative Colitis in Mice by Regulating Inflammation and Lymphocyte Apoptosis [J]. Frontiers in Immunology, 2017, 8: 905. (SCI，JCR一区，IF: 5.085).

  [7] Jian Liang#, Shuxian Chen#, Song Huang, et al. Evaluation of toxicity studies of flavonoid fraction of Lithocarpus polystachyus, Rehd in rodents [J]. Regulatory Toxicology and Pharmacology, 2017, 88: 283-290.(SCI, JCR一区，IF: 2.652).