[1] Xiaocui Li#, Qi Liang#, Caiyan Wang, Huawei Qiu, Tingting Lin, Wentao Li, Rong Zhang, Zhongqiu Liu, Lijun Zhu*. Role of P-glycoprotein in Regulating the Efficacy, Toxicity and Pharmacokinetics of Yunaconitine. Current Drug Metabolism. 2024;25(5):317-329.
[2] Caiyan Wang#, Xiaojun Teng#, Chuang Wang, Binjie Liu, Runze Zhou, Xueyu Xu, Huawei Qiu, Yu Fu, Rongjin Sun, Zuhui Liang, Rong Zhang, Zhongqiu Liu*, Lin Zhang*, Lijun Zhu*. Insight into the mechanism of Xiao-Chai-Hu-Tang alleviates irinotecan-induced diarrhea based on regulating the gut microbiota and inhibiting Gut β-GUS. Phytomedicine.2023. 120: 155040.
[3] Xiaocui Li, Weiqing Hou, Tingting Lin, Jiadong Ni, Huawei Qiu, Yu Fu, Zhongxiang Zhao, Caihua Yang, Na Li, Hua Zhou, Rong Zhang, Zhongqiu Liu, Ling Fu*, Lijun Zhu*. Neoline, fuziline, songorine and 10-OH mesaconitine are potential quality markers of Fuzi: In vitro and in vivo explorations as well as pharmacokinetics, efficacy and toxicity evaluations. Journal of Ethnopharmacology. 303 (2023) 115879.
[4] Xiaocui Li#, Yu Fu#, Huawei Qiu, Xueyu Xu, Tingting Lin, Weiqing Hou, Weiying Chen, Rong Zhang, Zhongqiu Liu, Lijun Zhu*. Clinical poisoning events involving yunaconitine may be highly correlated with metabolism-based interactions: A critical role of CYP3A4. Food and Chemical Toxicology. 2023 (179): 113989
[5] Xiaocui Li, Xiaojun Ou, Jiadong Ni, Yihong Xu, Huilin Zuo, Yu Fu, Caihua Yang, Zhongxiang Zhao, Na Li, Hua Zhou, Rong Zhang, Zhongqiu Liu, Ling Fu*, Lijun Zhu*. Bulleyaconitine A is a sensitive substrate and competitive inhibitor of CYP3A4: One of the possible explanations for clinical adverse reactions. Toxicology and Applied Pharmacology. 445(2022) 116024.
[6] Yuanyuan Liu#, Yiyan Lu#, Xiaoyan Li, Zerong Zhang, Lizhu Sun, Ying Wang, Zhuoru He, Zhongqiu Liu*, Lijun Zhu*, Ling Fu*. Kaempferol suppression of acute colitis is regulated by the efflux transporters BCRP and MRP2. European Journal of Pharmaceutical Sciences. 179 (2022) 106303. PMID: 36252521
[7] Xiaocui Li#, Xiaowen Ou#, Guangkuo Luo, Xiaojun Ou, Yusha Xie, Mengdi Ying, Wei Qu, Huilin Zuo, Xiaoxiao Qi, Ying Wang, Zhongqiu Liu*, Lijun Zhu*. Mdr1a, Bcrp and Mrp2 regulate the efficacy and toxicity mesaconitine and hypaconitine by altering their tissue accumulation and in vivo residence. Toxicology and Applied Pharmacology. 2020, 409: 115332
[8] Xiaocui Li, Yushan Xie, Wei Qu, Xiaojun Ou, Xiaowen Ou, Chuang Wang, Xiaoxiao Qi, Ying Wang, Zhongqiu Liu*, Lijun Zhu*. Breast cancer resistance protein and multidrug resistance protein 2 mediate the disposition of leonurine-10-O-β-glucuronide. Current Drug Metabolism.2020, 21(13): 1060-1067
[9] Rongjin Sun#, Lijun Zhu#, Li Li, Wenjie Song, Xia Gong, Xiaoxiao Qi, Ying Wang, Romi Ghose, Song Gao*, Ming Hu*, Zhongqiu Liu*. Irinotecan-mediated diarrhea is mainly correlated with intestinal exposure to SN-38: Critical role of gut Ugt. Toxicology and Applied Pharmacology. 2020, 398: 115032
[10] Lin Zhang#, Lijun Zhu#, Wei Qu, Fang Wu, Ming Hu, Wei Xie, Zhongqiu Liu*, Caiyan Wang*. Insight into Tartrate inhibition patterns in vitro and in vivo based on cocrystal structure with UDP-glucuronosyltransferase 2B15. Biochemical Pharmacology, 2020, 172: 113753
[11] Yuhuan Li, Wenjie Song, Xiaojun Ou, Guangkuo Luo, Yushan Xie, Rongjin Sun, Ying Wang, Xiaoxiao Qi, Ming Hu, Zhongqiu Liu*, Lijun Zhu*. Breast cancer resistance protein and multidrug resistance protein 2 determine the disposition of esculetin-7-O-glucuronide and 4-Methylesculetin-7-O-glucuronide. Drug Metablism & Disposition. 2019, 47 (3): 203-214
[12] Yuhuan Li, Linlin Lu, Liping Wang, Wei Qu, Wenqin Liu, Yushan Xie, Hongming Zheng, Ying Wang, Xiaoxiao Qi, Ming Hu*, Lijun Zhu*, Zhongqiu Liu*. Interplay of efflux transporters with glucuronidation and its impact on subcellular aglycone and glucuronide disposition: a case study with kaempferol. Molecular Pharmaceutics. 2018, 15(12): 5602-5614.
